Fig. 4
KDM5B knockdown reduces the tumor burden in vivo. a-c Both pSUPER-sh370 and pSUPER-sh2531 knockdown of KDM5B suppressed the tumorigenicity of Hep-3B cells in nude mice (n = 6), as compared with the negative control pSUPER-shNC. Tumors were weighed (b) and tumor volume (c) was evaluated every 3 days. The data were presented as the mean ± SD (n = 3), ** P < 0.01