Fig. 5

Effect of the TNF-α-CCR7 axis on the directional migration of GBC cells. a Migratory ability of the group that contained NOZ cells in the upper chamber only, without HDLECs in the lower chamber. b NOZ cells in the upper chamber and HDLECs in the lower chamber. c NOZ cells treated with 20 ng/mL TNF-α in the upper chamber and HDLECs in the lower chamber. d LV-shNC cells treated with 20 ng/mL TNF-α in the upper chamber and HDLECs in the lower chamber. e LV-shCCR7 cells treated with 20 ng/mL TNF-α in the upper chamber and HDLECs in the lower chamber. f Numbers of migrated cells in all 5 groups (*P < 0.05)