Table 1 miRNA involvement in CRC development, diagnosis and therapy

miR-324-5p,miR-21,miR-181b-1,miR-146,

Involved in regulation of NF-KB signaling in inflammation-related CRC

[30–50]

miR-126,miR-122,miR-192,miR-495,miR-671,

miR-106b,miR-30c,miR-130a

miR-16,miR-218,miR-34a

Involved in the cell proliferation and survival in CRC development

[51–59]

miR-34a,miR-148,miR-339-5p,miR-504,miR-23a,miR-129,miR-365,miR-345

Involved in the cell death in CRC development

[62–74]

miR-29a,miR-29b,miR-29c,miR-200a,miR-200b,miR-200c,miR-141,miR-429,miR-132,miR-192,

Involved in the EMT in CRC development

[79–95]

miR-335,miR-34a

miR-214,miR-155,miR-483,miR-133a,miR-145,

Involved in the tumor invasion and metastasis in CRC development

[96–112]

miR-21,miR-92a,miR-17-5p,miR-221,miR-499-5p,miR-182

miR-92a-3p,miR-29a,miR-17-3p,miR-221,

Involved in the clinical diagnosis of CRC

[123–129]

miR-19a-3p,miR-223-3p,miR-422a,miR-143,

miR-145,miR-21,miR-106a,miR-92a, miR-144

miR-135b,miR-27b,miR-4689,miR-483-5p,

Involved in the therapy of CRC

[131–152]

miR-551a,miR-34a,miR-22,miR129,miR-365,

miR-143,miR-21,miR-23a,miR-124