Fig. 3

Subpopulation Treatment Effect Pattern Plot (STEPP) Analysis of Ki67 assay according to histology: Prognostic Relevance for resected early stage pure and mixed invasive lobular carcinoma (ILC); Panel a: differences in Disease-Free Survival (DFS) rates at 60 months, between patients with pure and mixed (ductal-lobular) ILC according to patients’ subpopulations clustered by Ki67 (%) [the solid line above 0 on the y-axis indicates better DFS at 60 months for mixed ILC compared with pure ILC as values of Ki67 increase from left to right on the x-axis]; Panel b: DFS rates at 60 months of patients with pure and mixed ILC according to patients’ subpopulations clustered by Ki67 (%)