Subpopulation Treatment Effect Pattern Plot (STEPP) analysis of Ki67 assay according to histology: prognostic relevance for resected early stage ‘pure’ and ‘mixed’ lobular breast cancer

Table 3 Multivariate analysis

	Disease-free survival			Overall survival
Variables	HR	95 % CI	p-value	HR	95 % CI	p-value
Lymph-node status (Positive vs negative)	4.57	2.14–9.75	<0.0001	5.38	2.26–12.79	<0.0001
Ki67 (>21 % vs ≤21 %)	3.61	1.35–9.63	0.010	12.58	4.13–38.23	<0.0001
Radiotherapy (No vs Yes)	2.72	1.10–4.66	0.026	2.1	0.89–4.91	0.087
Age (>60 year vs ≤60 year)	-	-	-	3.74	1.53–9.13	0.004

Legend – Table 3: HR Hazard Ratio, CI confidence intervals, vs versus, yrs years

ISSN: 1756-9966