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Table 2 Isobologram analysis of NVP-Bez235 in combination with lenalidomide

From: Low dose of lenalidmide and PI3K/mTOR inhibitor trigger synergistic cytoxicity in activated B cell-like subtype of diffuse large B cell lymphoma

Cell lines Bez235 (nM) Len (μM) CI
Su-DHL2 5 0.5 0.306
  10 1 0.391
  20 2 0.695
  40 4 1.193
OCI-Ly3 5 0.5 0.402
  10 1 0.464
  20 2 0.694
  40 4 1.062
OCI-Ly10 5 0.5 0.76
  10 1 0.607
  20 2 0.768
  40 4 1.165