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Table 2 Isobologram analysis of NVP-Bez235 in combination with lenalidomide

From: Low dose of lenalidmide and PI3K/mTOR inhibitor trigger synergistic cytoxicity in activated B cell-like subtype of diffuse large B cell lymphoma

Cell lines

Bez235 (nM)

Len (μM)

CI

Su-DHL2

5

0.5

0.306

 

10

1

0.391

 

20

2

0.695

 

40

4

1.193

OCI-Ly3

5

0.5

0.402

 

10

1

0.464

 

20

2

0.694

 

40

4

1.062

OCI-Ly10

5

0.5

0.76

 

10

1

0.607

 

20

2

0.768

 

40

4

1.165

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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