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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Targeted p53 activation by saRNA suppresses human bladder cancer cells growth and metastasis

Fig. 3

dsP53-285 suppresses bladder cancer cells migration and invasion. T24 and EJ cells were transfected with 50 nM of the indicated dsRNAs for 72 h. a Representative wound healing images were pictured at 0, 12 and 24 h. b The relative distances between wound edges of bladder cancer cells at 0, 12 and 24 h. c Representative photographs of transwell assay (×200). d Number of migrated and invaded cells was quantified in 5 random images from each treatment group. Results are plotted as percent (%) relative to dsControl group. e Representative bioluminescent images of lungs of nude mice at the 30th days after intravenous injection. f Quantification analysis of fluorescence signal from captured bioluminescence images. * P < 0.05, * P < 0.01 and *** P < 0.001 compared to dsControl or Lenti-dsControl group

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