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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivo

Fig. 3

t-AUCB induces cell cycle G1 phase arrest. a, b: U251 and U87 cells were treated with DMSO (vehicle control), 10 μM or 150 μM t-AUCB for 48 h. 10 μM or 150 μM t-AUCB treated cells exhibited G1 phase proportion increase, 150 μM t-AUCB also induces S phase proportion decrease (**P < 0.01, *P < 0.05, # P > 0.05). c: The expression levels of c-Myc, Cdc25A, Cyclin D1, CDK4 and CDK6 were decreased in 150 μM treated cells. d: The expression levels of MCM3 and MCM7 were decreased in 150 μM treated cells. β-actin served as loading control. The protein intensity of the immunoblotting band was quantified by ImageJ and represented by the relative value compare with loading control (1.00)

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