Skip to main content

Table 2 Univariate and multivariate logistic regression models evaluating the impact of the YAPpos/YAPstroma phenotype on pCR (N = 61)

From: Topographic expression of the Hippo transducers TAZ and YAP in triple-negative breast cancer treated with neoadjuvant chemotherapy

   Univariate regression model Multivariate regression modela
OR (95 % CI) p-value OR (95 % CI) p-value
Age >49 vs ≤49 5.35 (1.51–19.03) 0.010 7.57 (1.81–31.65) 0.006
Stage III vs II 0.65 (0.19–2.16) 0.481   
Grade III vs II 1.66 (0.54–5.12) 0.380   
Ki-67 ≥60 vs <60 0.23 (0.07–0.76) 0.016 0.24 (0.06–0.94) 0.041
YAPpos/YAPstroma YAPpos/YAPstroma vs other combinations 5.23 (1.06–25.70) 0.042 7.13 (1.23–41.41) 0.029
  1. aAdjusted for Age, Ki-67 and YAPpos/YAPstroma