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Table 3 Uni- and multivariate Cox regression models of disease-free survival in TNBC patients (N = 57) considering a model of double positivity for TAZ and YAP

From: Topographic expression of the Hippo transducers TAZ and YAP in triple-negative breast cancer treated with neoadjuvant chemotherapy

   Univariate regression model Multivariate regression modela
HR (95 % CI) p-value HR (95 % CI) p-value
Age >49 vs ≤49 1.17 (0.47–2.88) 0.738   
Stage III vs II 1.17 (0.44–3.09) 0.751   
Grade III vs I-II 1.71 (0.65–4.52) 0.278   
pCR no vs yes 4.36 (1.00–18.99) 0.050 3.81 (0.87–16.71) 0.076
Ki-67 ≥60 vs <60 0.44 (0.16–1.17) 0.099   
TAZ/YAP TAZpos/YAPpos vs other combinations 3.44 (1.39–8.48) 0.007 3.07 (1.24–7.61) 0.016
  1. aAdjusted for pCR and TAZ/YAP