Fig. 3
CTNND1 promotes proliferative capacity of HCC cells both in vitro and in vivo. a The expression of CTNND1 protein was measured by Western blotting in the SK-Hep-1-shCTNND1s cell line and theirs control cells. b The expression of CTNND1 mRNA was measured by qRT-PCR in the SK-Hep-1-shCTNND1s cell line and theirs control cells. c The expression of CTNND1 protein was measured by Western blotting in the SNU-449-CTNND1 cell line and its control cells. d The expression of CTNND1 mRNA was measured by qRT-PCR in the SNU-449-CTNND1 cell line and its control cells. e The proliferation of the SK-Hep-1-shCTNND1s cell line and theirs control cells was examined by MTT assay. f The proliferation of the SNU-449-CTNND1 cell line and its control cells was examined by MTT assay. g Representative images of SK-Hep-1-shCTNND1 #1 or its control cell tumors by subcutaneous injection. h The weight of tumors formed by SK-Hep-1-shCTNND1 #1 cells or its control cells at harvest. i Representative images of SNU-449-CTNND1 cell or control cell tumors by subcutaneous injection. j The weight of tumors formed by SNU-449-CTNND1 cells or its control cells at harvest. **, P < 0.01 is based on the Student t test. All results are from three independent experiments. Error bars, SD