Fig. 4

CTNND1 promotes migratory and invasive capacities of HCC cells in vitro. a The SK-Hep-1-shCTNND1 #1 cell line and its control cells were subjected to wound-healing assays; the uncovered areas in the wound-healing assays were quantified as a percentage of the original wound area. b The SK-Hep-1-shCTNND1 #1 cell line and its control cells were subjected to Transwell migration (top), and Matrigel invasion assays (bottom). Quantification of migrated cells through the membrane and invaded cells through Matrigel of each cell line are shown as proportions of their vector controls. c The SNU-449-CTNND1 cell line and its control cells were subjected to wound-healing assays. The uncovered areas in the wound-healing assays were quantified as a percentage of the original wound area. d The SNU-449-CTNND1 cell line and its control cells were subjected to Transwell migration (top) and Matrigel invasion assays (bottom). Quantification of migrated cells through the membrane and invaded cells through Matrigel of each cell line are shown as proportions of their vector controls. **, P < 0.01 is based on the Student t test. All results are from three independent experiments. Error bars, SD