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Table 1 CTNND1 staining and clinicopathologic characteristics of 289 hepatocellular carcinoma patients

From: Overexpression of CTNND1 in hepatocellular carcinoma promotes carcinous characters through activation of Wnt/β-catenin signaling

Variables

CTNND1 staining

Total

P a

Low

High

Age (y)

   

0.667

  ≤ 50

89 (77 %)

27 (23 %)

116

  > 50

131 (76 %)

42 (24 %)

173

Sex

   

0.262

 Male

163 (69 %)

27 (31 %)

235

 Female

42 (78 %)

12 (22 %)

54

HBsAg

   

0.231

 Negative

53 (65 %)

28 (35 %)

81

 Positive

151 (73 %)

57 (27 %)

208

HCV

   

0.135

 Negative

185 (76 %)

57 (24 %)

242

 Positive

31 (66 %)

16 (34 %)

47

AFP

   

0.634

  ≤ 20

64 (69 %)

27 (31 %)

93

  > 20

136 (68 %)

60 (32 %)

196

γ-GT(U/L)

   

0.187

  ≤ 54

113 (81 %)

26 (19 %)

139

  > 54

110 (73 %)

40 (27 %)

150

Liver cirrhosis

   

0.766

 No

41 (66 %)

22 (34 %)

62

 Yes

159 (70 %)

68 (30 %)

227

Tumor diameter (cm)

   

0.028

  ≤ 5

178 (70 %)

77 (30 %)

255

  > 5

15 (44 %)

19 (56 %)

34

Microvascular invasion

   

<0.001

 Absence

92 (80 %)

23 (20 %)

115

 Present

63 (36 %)

111 (64 %)

174

Tumor encapsulation

   

0.196

 Complete

83 (62 %)

50 (38 %)

133

 None

91 (58 %)

65 (42 %)

156

Tumor differentiation

   

<0.001

 I + II

135 (71 %)

56 (29 %)

191

 III + IV

31 (32 %)

67 (68 %)

98

TNM stage

   

0.307

 I

161 (69 %)

73 (31 %)

234

 II + III

32 (58 %)

23 (42 %)

55

  1. Abbreviations: HBsAg hepatitis B surface antigen; AFP α-fetoprotein; γ-GT γ-glutamyl transferase; TNM, tumor-nodesmetastasis
  2. a p-value < 0.05 was considered statistically significant. p-values were calculated using the Pearson chi-square test