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Table 1 CTNND1 staining and clinicopathologic characteristics of 289 hepatocellular carcinoma patients

From: Overexpression of CTNND1 in hepatocellular carcinoma promotes carcinous characters through activation of Wnt/β-catenin signaling

Variables CTNND1 staining Total P a
Low High
Age (y)     0.667
  ≤ 50 89 (77 %) 27 (23 %) 116
  > 50 131 (76 %) 42 (24 %) 173
Sex     0.262
 Male 163 (69 %) 27 (31 %) 235
 Female 42 (78 %) 12 (22 %) 54
HBsAg     0.231
 Negative 53 (65 %) 28 (35 %) 81
 Positive 151 (73 %) 57 (27 %) 208
HCV     0.135
 Negative 185 (76 %) 57 (24 %) 242
 Positive 31 (66 %) 16 (34 %) 47
AFP     0.634
  ≤ 20 64 (69 %) 27 (31 %) 93
  > 20 136 (68 %) 60 (32 %) 196
γ-GT(U/L)     0.187
  ≤ 54 113 (81 %) 26 (19 %) 139
  > 54 110 (73 %) 40 (27 %) 150
Liver cirrhosis     0.766
 No 41 (66 %) 22 (34 %) 62
 Yes 159 (70 %) 68 (30 %) 227
Tumor diameter (cm)     0.028
  ≤ 5 178 (70 %) 77 (30 %) 255
  > 5 15 (44 %) 19 (56 %) 34
Microvascular invasion     <0.001
 Absence 92 (80 %) 23 (20 %) 115
 Present 63 (36 %) 111 (64 %) 174
Tumor encapsulation     0.196
 Complete 83 (62 %) 50 (38 %) 133
 None 91 (58 %) 65 (42 %) 156
Tumor differentiation     <0.001
 I + II 135 (71 %) 56 (29 %) 191
 III + IV 31 (32 %) 67 (68 %) 98
TNM stage     0.307
 I 161 (69 %) 73 (31 %) 234
 II + III 32 (58 %) 23 (42 %) 55
  1. Abbreviations: HBsAg hepatitis B surface antigen; AFP α-fetoprotein; γ-GT γ-glutamyl transferase; TNM, tumor-nodesmetastasis
  2. a p-value < 0.05 was considered statistically significant. p-values were calculated using the Pearson chi-square test