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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Enhancement of anti-tumor effects of 5-fluorouracil on hepatocellular carcinoma by low-intensity ultrasound

Fig. 7

The anti-tumor effects on HCC after the treatment of low-intensity ultrasound combined with 5-FU. a Tumor-bearing nude mice in the Control, US alone, 5-FU alone, and US + 5-FU groups. b Overall survival analysis results by the Kaplan-Meier survival curves (log-rank test, p = 0.001). c Representative histopathological changes in the Control, US alone, 5-FU alone, and US + 5-FU groups. Representative TUNEL-positive (d) and PCNA-positive (e) cells from mice of different treatment groups. The apoptotic index (AI) and relative cell proliferation were calculated as the number of positive cells for each group. Data was presented as the mean ± SD (n = 6, ★ p < 0.05 vs. other three groups)

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