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Table 2 Positivity and composite scores of TET3 in ovarian cancer tissues

From: TET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells

    Immunohistochemical composite scores  
Subtypes of ovarian cancer Overall Positivitya P valueb Mean SD P valuec
Normal (n = 14) 12 (85.7 %)   1.21 0.90  
Ca (n = 68) 52 (76.5 %) 0.724 0.72 0.72 0.0269*
 EOC      
  Serous cancer (n = 37) 29 (78.4 %) 0.707 0.71 0.70 0.0401*
  Mucinous cancer (n = 8) 8 (100 %) 0.515 1.16 0.78 0.8932
  Endometrioid cancer (n = 5) 4 (80 %) 1.000 1.10 1.06 0.8182
  Clear cell cancer (n = 5) 5 (100 %) 1.000 0.86 0.67 0.4345
 Germ cell tumor      
  Dysgerminomas (n = 3) 1 (33.3 %) 0.121 0.10 0.17 0.0541
  Endodermal sinus tumor (n = 1) 0     
  Immaure teratomas (n = 2) 1 (50.0 %) 0.350 0.40 0.56 0.2402
  Granulosa cell tumor (n = 3) 2 (66.7 %) 0.456 0.40 0.35 0.1508
  1. aPercentage of cases with more than 5 % positive cells. bFisher’s Exact Test (two-tailed), compared with the positive percentage of normal tissues. ct-test (two-tailed), compared with the composite scores of normal cases. * P < 0.05