Fig. 2

Modulation of apoptosis related signaling proteins using antibody array assay. Eight tumor samples were randomly selected from each group for this analysis. Total protein was extracted from the tumor tissues. A slide-based antibody array was used for simultaneous detection of 19 signaling molecules (c and d) involved in stress response and apoptosis using a PathScan Stress and Apoptosis Signaling Array kit. Each protein was arranged in duplicate. The names of the proteins with significant changes in concentration were indicated on the images (a) and their concentrations quantified (b). Data are presented as mean ± SD. GT, green tea; Q, quercetin; Doc 5, docetaxel at 5 mg/kg iv. Columns with different letters represent significant difference between treatments (P < 0.05)