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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model

Fig. 1

Graphical representation of the constructed and generated non-armed control oncolytic adenovirus (Ad-ΔB) and oncolytic adenovirus armed with human TRAIL gene (Ad-ΔB/TRAIL) or human IL-12 gene (Ad-ΔB/IL-12). TRAIL or IL-12 gene was incorporated in the E3 region of the viral backbone under the transcriptional control of the human cytomegalovirus (CMV) promoter

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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