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Table 2 SH2B1 expression and clinicopathological features in non-small cell lung cancer (NSCLC) patients

From: MicroRNA-361-3p suppresses tumor cell proliferation and metastasis by directly targeting SH2B1 in NSCLC

Variables

n

SH2B1 expression

 

+

++

+++

p value*

Gender

 Male

67

16

16

35

 

 Female

24

3

6

15

0.486

Age(years)

  > 55

56

14

10

32

 

 ≦55

35

5

12

18

0.156

Smoking history

 Yes

54

14

11

29

 

 No

37

5

11

21

0.293

Pathological type

 Adenocarcinoma

54

15

12

27

 

 Squamous carcinoma

37

4

10

23

0.063

Tumor differentiation

 High

22

7

6

9

 

 Middle

58

10

14

34

 

 Low

11

2

2

7

0.518

Tumor location

 Right lung

45

11

10

24

 

 Left lung

46

8

12

26

0.696

Tumor size(cm)

  > 3

54

8

12

34

 

 ≦3

37

11

10

16

0.129

Lymphatic metastasis

 Yes

42

0

10

32

 

 No

49

19

12

18

<0.001

TNM classification

 I

43

18

10

15

 

 II

22

1

9

12

 

 III + IV

26

0

3

23

<0.001

  1. Abbreviations: TNM tumor-node-metastasis
  2. * χ2test