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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: FLIPL is critical for aerobic glycolysis in hepatocellular carcinoma

Fig. 2

FLIPL expression positively correlated with SGLT1 expression in HCC. GLUT1 and SGLT1 expression were determined by real-time PCR (a) and immunoblot analysis (b) in HepG2 cells with FLIPL knockdown treatment. Left panel: Immunoblotting. Right panel: Densitometric quantification of the data in b, normalized to β-tubulin. Data are the mean ± S.E.M. from three independent experiments. *p < 0.05, **p < 0.01 versus the control group. c IHC staining of FLIPL and SGLT1 in adjacent normal and liver cancer samples from patients at different stages. Case 1 is from a stage II patient, and Case 2 is from a stage I patient. Bar = 200 μm. (d) and (e) Quantification of the expression levels of FLIPL and SGLT1 in human HCC samples. **p < 0.01 versus adjacent normal tissues. f Correlation between FLIPL and SGLT1 expression with linear regression and Pearson’s correlation significance (p < 0.01)

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