From: The comparison of clinical and biological characteristics between IDH1 and IDH2 mutations in gliomas
Pathological diagnosis | WHO grade | n = 811 | IDH1 mutation No. (%) | IDH2 mutation No. (%) | IDH mutation total No. (%) |
---|---|---|---|---|---|
Diffuse astrocytoma | II | 193 | 138 (71.5) | 2 (1.0) | 140 (72.5) |
Anaplastic astrocytoma | III | 39 | 14 (35.9) | 0 (0) | 14 (35.9) |
Oligodendroglioma | II | 49 | 38 (77.6) | 3 (6.1) | 41 (83.7) |
Anaplastic oligodendroglioma | III | 27 | 19 (70.4) | 1 (3.7) | 20 (74.1) |
Oligoastrocytoma | II | 186 | 147 (79.0) | 9 (4.8) | 156 (83.8) |
Anaplastic oligoastrocytoma | III | 83 | 47 (56.6) | 1 (1.2) | 48 (57.8) |
Subtotal (grades II and III) | Â | 577 | 403 (69.8) | 16 (2.8) | 419 (72.6) |
Primary GBM | IV | 205 | 29 (14.1) | 1 (0.5) | 30 (14.6) |
Secondary GBM | IV | 29 | 16 (55.2) | 1 (3.4) | 17 (58.6) |
Subtotal (Glioblastoma) | IV | 234 | 45 (19.2) | 2 (0.9) | 47 (20.1) |
Total | Â | 811 | 448 (55.2) | 18 (2.2) | 466 (57.4) |