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Table 3 Molecular characteristics according to IDH mutation in glioma

From: The comparison of clinical and biological characteristics between IDH1 and IDH2 mutations in gliomas

Molecular Characteristic   IDH1-Mutated IDH2-Mutated IDH1/IDH2-WT P (IDH1-Mutated VS IDH1/IDH2-WT) P (IDH2-Mutated VS IDH1/IDH2-WT) P (IDH1-Mutated VS IDH2-Mutated)
PTEN Mutation 6 0 43 <0.001 0.098 0.605
  Wild-type 314 14 218    
  NA 128 4 84    
1p/19q Co-deletion Absent 341 9 307 <0.001 <0.001 <0.05
  Present 106 9 34    
  NA 1 0 1    
P53 Mutation 215 0 232 <0.001 0.154 <0.05
  Wild-type 115 14 34    
  NA 118 4 79    
ATRX Mutation 13 0 15 0.084 0.638 0.728
  Wild-type 107 5 102    
  NA 328 13 228