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Table 3 Molecular characteristics according to IDH mutation in glioma

From: The comparison of clinical and biological characteristics between IDH1 and IDH2 mutations in gliomas

Molecular Characteristic

 

IDH1-Mutated

IDH2-Mutated

IDH1/IDH2-WT

P (IDH1-Mutated VS IDH1/IDH2-WT)

P (IDH2-Mutated VS IDH1/IDH2-WT)

P (IDH1-Mutated VS IDH2-Mutated)

PTEN

Mutation

6

0

43

<0.001

0.098

0.605

 

Wild-type

314

14

218

   
 

NA

128

4

84

   

1p/19q Co-deletion

Absent

341

9

307

<0.001

<0.001

<0.05

 

Present

106

9

34

   
 

NA

1

0

1

   

P53

Mutation

215

0

232

<0.001

0.154

<0.05

 

Wild-type

115

14

34

   
 

NA

118

4

79

   

ATRX

Mutation

13

0

15

0.084

0.638

0.728

 

Wild-type

107

5

102

   
 

NA

328

13

228

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