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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: RNF8 promotes epithelial-mesenchymal transition of breast cancer cells

Fig. 3

RNF8 inactivates GSK3β and increases β-catenin accumulation. a Western blotting analysis of EMT signaling hallmarks in MCF-7 cells infected with TG006 or TG006-RNF8 virus. β-actin was used as an internal standard. Quantification of each indicated protein expression was plotted (right panel). The result is shown from three independent experiments (Columns, mean; Bars, ± s.d. ***, p < 0.001; **, p < 0.01; *, p < 0.05; ns, no significance). b Western blotting analysis of EMT signaling hallmarks in MDA-MB-231 stable cell line expressed control (shRNA empty) or shRNF8-1 or shRNF8-2, β-actin was used as an internal standard. Quantification of each indicated protein expression was plotted in right panel (right panel). The result is shown from three independent experiments (Columns, mean; Bars, ± s.d. ***, p < 0.001; **, p < 0.01; *, p < 0.05; ns, no significance)

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