Fig. 4
From: RNF8 promotes epithelial-mesenchymal transition of breast cancer cells
RNF8 promotes cell migration in breast cancer. a The migration of MCF-7 cells infected with TG006 or TG006-RNF8 virus (upper; magnification, 10 ×) or MDA-MB-231 cells transfected by siControl or siRNF8-1 (bottom; magnification, 20 ×) were examined by transwell migration assay. Overexpression of RNF8 enhances the migration of MCF-7 cells. **, p < 0.01. The data represent the means ± s.d. of three independent experiments. b Wound healing scratch assay was performed to detect the migration of RNF8-depleted MDA-MB-231 cells described in A. magnification, 10 ×; Right, the relative migration rate was calculated by dividing the change in the distance between the scratch edges by the initial distance, ***, p <0.001