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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: RNF8 promotes epithelial-mesenchymal transition of breast cancer cells

Fig. 7

RNF8 expression is associated with breast cancer metastasis. a Representative examples showing higher RNF8 expression in the lymph node metastases than in the corresponding primary breast cancer tissues. case 1, cytoplasmic expression of RNF8; case 2, nuclear expression of RNF8. Magnification, 20 ×; scale bars: 20 μm; Inset, 40 ×. b Comparison of the RNF8 expression between breast cancer tissues and the corresponding lymph node metastases. LN > Bre, LN < Bre, and LN = Bre indicate RNF8 expression is higher, lower, or equal in metastatic lymph node compared with that of primary breast cancer; ‘Both negative’ means that the expression of RNF8 was not detectable in both metastatic lymph node and primary breast cancer tissues. The histographs show the percentage of cases with distinct expression pattern of cytoplasmic (Left) or nuclear (right) RNF8

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