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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: Long non-coding RNA ATB promotes glioma malignancy by negatively regulating miR-200a

Fig. 5

Repression of miR-200a abolished the sh-ATB induced inhibitory effects on glioma cells. a-b CCK-8 assay was performed to determine the proliferation after co-transfected with sh-ATB and miR-200a mimics or miR-200a inhibitors. *P < 0.05, **P < 0.01 vs. sh-control group; # P < 0.05 vs. sh-ATB group. c Colony formation assay was performed to detect the proliferation effect of U251 and A172 cells after co-transfected with sh-ATB and miR-200a mimics or miR-200a inhibitors. *P < 0.05, **P < 0.01 vs. sh-control group; # P < 0.05, ## P < 0.01 vs. sh-ATB group. d Invasion assay (use matrigel transwell chambers) in U251 and A172 cells was performed to determined cell invasiveness after co-transfected with sh-ATB and miR-200a mimics or miR-200a inhibitors. **P < 0.01 vs. sh-control group; # P < 0.05, ## P < 0.01 vs. sh-ATB group. Data are presented as mean ± SD from three independent experiments

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