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Table 1 miR-655-3p expression and clinicopathological features in hepatocellular carcinoma patients

From: MicroRNA-655-3p functions as a tumor suppressor by regulating ADAM10 and β-catenin pathway in Hepatocellular Carcinoma

Characteristics

miR-655-3p expression

p-value

Cases

Low

middle/High

Age (years)

 ≥ 53

43

27(62.8 %)

16(37.2 %)

0.69

 < 53

41

24(58.5 %)

17(41.5 %)

 

Gender

 Male

71

45(63.4 %)

26(36.6 %)

0.242

 Female

13

6(46.2 %)

7(53.8 %)

 

HBsAg status

 Positive

62

36(58.1 %)

26(41.9 %)

0.404

 Negative

22

15(68.2 %)

7(31.8 %)

 

AFP (ng/ml)

 ≥ 20

48

30(62.5 %)

18(37.5 %)

0.699

 < 20

36

21(58.3 %)

15(41.7 %)

 

Liver cirrhosis

 Yes

63

38(60.3 %)

25(49.7 %)

0.897

 No

21

13(61.9 %)

8(39.1 %)

 

Tumour size (cm)

 < 5

44

22(50 %)

22(50 %)

0.035*

 ≥ 5

40

29(72.5 %)

11(27.5 %)

 

PVTT

 Yes

9

9(100.0 %)

0(0.0 %)

0.028*

 No

75

42(56 %)

33(44 %)

 

TNM Classification

 I + II

50

24(48 %)

26(52 %)

0.004**

 III + IV

34

27(79.4 %)

7(20.6 %)

 

Tumour differentiation

 Well

37

21(56.8 %)

16(43.2 %)

0.721

 Moderate

34

21(61.8 %)

13(48.2 %)

 

 Poor

13

9(69.2 %)

4(30.8 %)

 

Metastasis

 Yes

33

27(81.8 %)

6(18.2 %)

0.001**

 No

51

24(47.1 %)

27(52.9 %)

 
  1. Abbreviations: AFP alpha-fetoprotein, HBsAg hepatitis B surface antigen, TNM tumor-node-metastasis, PVTT portal vein tumor thrombosis. * p<0.05; ** p<0.01