Fig. 2

Effects of the MUC4/Y-AMOP domain-deletion on the migration and invasion of PANC-1 derived sub-lines and the conditioned medium on the tube formation, proliferation, migration, and invasion of HUVEC. a Trans-well migration and Matrigel invasion assays of HUVEC were performed in the conditioned medium of different groups. b CCK8 assay. The OD value was used to assess the proliferation of HUVEC in the conditioned medium of different groups. c Tube formation assays of HUVEC. The area of network was calculated with Image Pro Plus 6.0. d Trans-well migration and Matrigel invasion assays of PANC-1 derived sub-lines. The number of cells that migrate or invade to the lower surface of the inserts chamber were stained and photographed. *P < 0.05, **P < 0.01