Fig. 6

Knockdown of HOXD-AS1 promotes apoptosis using ELISA assay. a, b Relative activities of caspase-3 in 5637 (P = 0.003) and T24 (P = 0.016) were shown after transfection with si-HOXD-AS1. c, d The activity of caspase-3 was increased significantly after transfection with tet-shRNA in 5637 (P = 0.001) and T24 cells (P = 0.002). Results represent the mean ± SD from three independent experiments