Fig. 1
From: Targeting microRNAs as key modulators of tumor immune response
Schematic representation of microRNA regulation in immune cell development and activity. MiRNAs have been demonstrated to function as important regulators of both innate and adaptive immunity, including differentiation and functions of different immune cell subsets. The most relevant miRNAs are included in the figure. The miRNAs in red boxes are involved in regulating the developmental transition indicated by the arrows, as well as the activity of cells in the immune system (full explanation in text). *MicroRNAs involved in negative regulation of immune cell development or function. HSC: Hematopoietic Stem Cell; CMP: Common Myeloid Progenitor; GMP: Granulocyte–Monocyte Progenitor; MEP: Megakaryocyte-Erythrocyte Progenitor; CLP: Common Lymphoid Progenitor; DC: Dendritic cell; aDC: activated Dendritic Cell; DN: Double Negative; DP: Double Positive; SP: Single Positive