Fig. 2

Clonogenic survival of MB cells after 6-day single drug treatment. Reproductive long-term survival was determined by clonogenic assays in three MB cell lines after 6-day treatment with: a) 5-aza-dC, b) VPA, c) SAHA, d) ATRA, e) ABC, f) RES. Five distinct drug concentrations were applied and values are normalized to untreated control. The experiment was performed once in sextuplicates. Data are presented as mean ± SEM. IC 90 values for combination experiments were calculated using Excel software and are shown in Table 1