Fig. 1

High miR-130b expression confers unfavorable prognosis of lung cancer patients. a MiR-130b expression in lung cancer tissues. b MiR-130b expression in relation to the expression of PPARγ, VEGF-A and BCL-2. c Representative TMA sections stained for PPARγ, VEGF-A and BCL-2 by immunohistochemistry (scale bar, 100 μm), and apoptosis by TUNEL assay (scale bar, 50 μm). d Correlations between miR-130b level and PPARγ, VEGF-A, BCL-2 or apoptosis. e A shorter overall survival time in patients with high miR-130b. NL, normal lung; AD, adenocarcinoma; SQ, squamous cell carcinoma; TUNEL, terminal deoxynucleotidyl transferase-mediated uridine 5’-triphosphate-biotin nick end labeling. *p < 0.05, #p < 0.001