Fig. 2
From: SYNJ2BP inhibits tumor growth and metastasis by activating DLL4 pathway in hepatocellular carcinoma
Immunohistochemistry of Synaptojanin 2 Binding Protein (SYNJ2BP) protein is down-regulated in HCC tissues and is closely related to patient survival. Here shows representative images: a, b SYNJ2BP expression level is strongly high in PTs. c SYNJ2BP expression scored as 0. d SYNJ2BP expression scored as 1+. e SYNJ2BP expression scored as 2+. f SYNJ2BP expression scored as 3+. Survival curves were calculated with the Kaplan-Meier method, differences were evaluated using log-rank test. g According to IHC results, patients were divided into low expression group (SYNJ2BP expression scored as 0 or 1+) and high expression group (SYNJ2BP expression scored as 2 or 3+). Results showed that HCC patients from the low expression group had poorer OS (P = 0.001) and DFS (P = 0.006) than those from the high expression group. Original magnification: 400× for (b); 100× for (a) and (c to f)