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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Nestin overexpression in hepatocellular carcinoma associates with epithelial-mesenchymal transition and chemoresistance

Fig. 1

Increased expression of Nestin in HCC tissue. a Representative immunohistochemical staining of Nestin protein in HCC tissues and adjacent non-tumor tissue (ANTT) (Original magnification: × 400). b The association between Nestin expression and chemotherapeutic response (FOLFOX regimens) was analyzed. More patients in low Nestin group achieved PR, SD, RR and DCR, and less PD, all P < 0.05. HCC patients with higher Nestin expression have poorer PFS (c) and OS (d) than those with lower Nestin expression. CR, PR, SD, PD, NE, RR and DCR represent complete response, partial response, stable disease, progressive disease, not evaluated, response rate (RR) and disease control rate (DCR) respectively. RR = CR + PR, DCR = CR + PR + SD

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