From: 1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis
Experimental model
Mouse strain
No. of mice/group
Total No. of used mice
Experimental metastasis (Fig. 1)
BALB/c Nude
7
21
Spontaneous metastasis (single drug treatment) (Fig. 2)
BALB/c
10
30
Matrigel plugs (Fig. 3)
9
36
Spontaneous metastasis (combined treatment) (Figs. 4 and 5)
50
