Fig. 5
From: Sam68 reduces cisplatin-induced apoptosis in tongue carcinoma
TUNEL assays was carried in two OTSCC cell lines, SCC-9 and SCC-25 (a, b) to test the anti-resistance and drug-resisstant. The results showed that Sam68 upregulation conferred resistance to OTSCC cells Sam68 upregulation enhanced the resistance of these cells to chemotherapeutics, DDP, and Sam68 downregulation dramatically enhanced the sensitivity of these cells to chemotherapeutics