Fig. 7
From: Sam68 reduces cisplatin-induced apoptosis in tongue carcinoma
TUNEL assays showed that cells from tumors showing Sam68 upregulation exhibited resistance to DDP, whereas cells derived from tumors showing Sam68 downregulation exhibited dramatically enhanced sensitivity to DDP (a). Western blot analysis showed that tumors derived from Sam68-overexpressing cells exhibited increased activation of caspase 9 and PARP cleavage in response to DDP (b)