A restricted signature of serum miRNAs distinguishes glioblastoma from lower grade gliomas

Table 1 General characteristics and clinicopathological features of brain tumor patients and control subjects

Variables		Controls(n = 15)	Gliomas(n = 22)	Meningiomas (n = 8)
Age	mean	51	54	61
Age	range	29–65	24–82	27–76
Gender	males	8	12	3
Gender	females	7	10	5
Neurological disorders^a		_	6	_
Grade	II/III	_	12	_
Grade	IV	_	10	_
IDH1 mutation^{b c}		_	6	_
IDH2 mutation^c		_	0	_
MGMT promoter methylated^d		_	12	_

^a Hemisyndrome, psychiatric disorders, cognitive disorders
^b mutation r132h
^c 19 out of 22 patients analyzed for this mutations ^d MGMT promoter was considered methylated if the percentage of methylation was >5 %
14 out of 22 patients analyzed for methylation

ISSN: 1756-9966