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Table 2 Clinical pathological characteristic of breast cancer patients associating with CLDN6 expression

From: DNA methylation of claudin-6 promotes breast cancer cell migration and invasion by recruiting MeCP2 and deacetylating H3Ac and H4Ac

Characteristic N CLDN6 Expression P value
High Low
Breast cancer tissues 30 7 (23.33 %) 23 (76.67 %)  
Pericarcinomatous tissues 10 10 (100 %) 0 (0 %) P < 0.05
Age (years)     
 20–40 9 2 (22.22 %) 7 (77.78 %)  
 40–60 14 3 (21.43 %) 11 (78.57 %)  
 60–80 7 2 (28.57 %) 5 (71.43 %) P > 0.05
Tumor status     
 T1 13 2 (15.38 %) 11 (84.62 %)  
 T2 12 4 (33.33 %) 8 (66.67 %)  
 T3 5 1 (20 %) 4 (80 %) P > 0.05
Clinical stage     
 Is-I 14 4 (28.57 %) 10 (71.43 %)  
 II-IV 16 3 (18.75 %) 13 (81.25 %) P > 0.05
Node status     
 + 19 2 (10.53 %) 17 (89.47 %)  
 – 11 5 (45.45 %) 6 (54.55 %) P < 0.05
  1. P value was measured with student’s t test. Significance of association was determined using a χ2 test