Fig. 1

The 80 genes that were significantly dysregulated in hepatocellular carcinomas according to four independent microarrays retrieved from the Oncomine database. a The top 40 genes that were significantly upregulated in four microarrays. b The top 40 genes that were significantly downregulated in four microarrays. The four microarrays cover a total of 386 cases of hepatocellular carcinomas and 327 cases of normal liver tissue: (1) Chen Liver Statistics, 104 cases of hepatocellular carcinoma and 76 cases of liver tissue; (2) Roessler Liver Statistics, 22 cases of hepatocellular carcinoma and 21 cases of liver tissue; (3) Roessler Liver 2 Statistics, 225 cases of hepatocellular carcinoma and 220 cases of liver tissue; (4) Wurmbach Liver Statistics, 35 cases of hepatocellular carcinoma and 10 cases of liver tissue. The rank for a gene is the median rank for that gene across each of the analyses. The P value given for a gene is for the median-ranked analysis. The genes labelled in red and in blue were significantly and consistently up- and downregulated in the four microarrays, respectively