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Table 1 Single-color staining with Propidium iodide

From: New derivatives of the antimalarial drug Pyrimethamine in the control of melanoma tumor growth: an in vitro and in vivo study

Mel501

Ctr

Pyr

Temozolomide

MBP 0.8ug/ml

MBP 8ug/ml

MBP 80ug/ml

 24 h

0.4

1

0.1

0.6

2

11.5

 48 h

1.2

4

4

2

3.6

14

 72 h

1

3.6

3

2.4

4.2

25

MeWo

Ctr

Pyr

Temozolomide

MBP 0.8ug/ml

MBP 8ug/ml

MBP 80ug/ml

 24 h

0.5

1

0.8

0.9

0.9

9.5

 48 h

0.8

0.5

1

1.6

1.4

15

 72 h

1

0.7

0,8

1

1

18

  1. Numbers in the columns represent the average percentage of AV negative/PI positive (necrotic cells) obtained by 10 different experiments