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Table 1 Genetic status and p53-MCL rate of LCLs from familial breast and ovarian cancer

From: Detection of ATM germline variants by the p53 mitotic centrosomal localization test in BRCA1/2-negative patients with early-onset breast cancer

 

BRCA1

BRCA2

CHK2

PALB2

ATM

p53-MCL%

BR36

wt

mut

nt

nt

nt

80

BR13

wt

mut

nt

nt

nt

76

BR409-3

mut

wt

nt

nt

nt

97

BR324-1

mut

wt

nt

nt

nt

85

BR404-1

mut

wt

wt

wt

wt

76

BR317

mut

wt

nt

nt

mut

50

BR377

wt

wt

wt

wt

mut

50

BR60-1

wt

wt

wt

wt

wt

71

BR107-1

wt

wt

wt

wt

wt

90

BR362-1

wt

wt

wt

wt

wt

92

BR494

wt

wt

wt

wt

wt

86

BR38

wt

wt

wt

wt

wt

91

BR48

wt

wt

wt

wt

wt

70

BR278-1

wt

wt

wt

wt

wt

80

BR501

wt

wt

mut

wt

wt

80

  1. wt wild type, mut mutated, nt not tested