Fig. 5

Loss of IL-6 in monocytes decreases spontaneous liver cancer in mdr2^−/− mice. a The gross view of spontaneous liver cancer in mice. b The mean ratio of the LW/BW between mice with different bone marrow transplantation. Data are presented as mean ± s.e.m, n ≥ 6; ***p < 0.001. c Greatly less infiltrated macrophages in tumor tissue of Mdr2 ^−/− & IL6 ^−/−mice. Scale bar = 50 μm