Fig. 5
From: Targeting interleukin-1 receptor-associated kinase 1 for human hepatocellular carcinoma
The IRAK1 inhibitor arrested the cell cylce and induced apoptosis in HCC cells. a Flow cytometry assays of cell cycle arrest in SMMU-7721 cell line, with treatment of IRAK1/4 inhibitors (0, 10 μM, 20 μM) for 24 h and 48 h and staining with PI. b The fractions of cells in each phase of the cell cycle including G0/G1, S and G2/M phases. c Flow cytometry assays of cell apoptosis in SMMU-7721 cell line, with treatment of the IRAK1/4 inhibitor (20 μM) for 24 h and 48 h and staining with Annexin V and PI