Fig. 1From: Epidermal growth factor (EGF) receptor-ligand based molecular staging predicts prognosis in head and neck squamous cell carcinoma partly due to deregulated EGF- induced amphiregulin expressionHigh tumorous mRNA levels of EGFR-ligands predicted poor prognosis in HNSCC patients. HNSCC patients with higher than median tumorous AREG (a), EGF (b), HBEGF (c) or BTC (d) mRNA levels had lower five-year survival rate compared to patients with lower than median expression levels (Kaplan-Meier curve, Log rank test). The mRNA levels are measured as fragments per kilobase per million mapped reads (FPKM)Back to article page