From: TIMP1 is a prognostic marker for the progression and metastasis of colon cancer through FAK-PI3K/AKT and MAPK pathway
TIMP1 expression
Tissue sample
n
Negative
Weak
Positive
P-value
Normal mucosa
94
57 (60.6Â %)
22 (23.4Â %)
15 (16.0Â %)
<0.01*
Cancerous tissue
44 (46.8Â %)
24 (25.5Â %)
26 (27.7Â %)
LNM tissue
36
7 (19.4Â %)
11 (30.6Â %)
18 (50.0Â %)