Fig. 7
From: Non-benzoquinone geldanamycin analogs trigger various forms of death in human breast cancer cells
DHQ3 and 17-DR significantly delays MDA-MB-231 tumor growth. a Representative tumors from each treatment group. b Body weight of the mice. c Tumor volume of the mice. d Tumor weights after DHQ3, 17-DR and DDP treatment. e In vivo hepatotoxicity evaluation of DHQ3 and 17-DR in nude mice. The AST and ALT were determined by Assay Kit. The blood serum samples were treated according to the manufacturer’s instruction. And the AST and ALT activities are expressed as U/L. f H&E-stained sections of the tumor, liver, lung and kidney from the mice after treatment