Fig. 7
From: Over-expression of the long non-coding RNA HOTTIP inhibits glioma cell growth by BRE
Over-expression of BRE and HOTTIP altered the expression of P53, cyclin A and CDK2 proteins. a Over-expression of BRE reduced P53 protein expression and increased cyclin A and CDK2 expression as assessed by Western blot analysis in the U87-MG and U118-MG glioma cell lines. b Over-expression of HOTTIP increased P53 protein expression and decreased BRE, cyclin A and CDK2 protein expression as assessed by Western blot analysis in U87-MG and U118-MG glioma cell lines. β-actin was used as a reference. The results represent data from at least three independent experiments expressed as the mean ± SD.*P < 0.05