Fig. 2

High miR-501-5p predicts poor prognosis. a Real-time PCR analysis of miR-501-5p expression in 112 freshly collected gastric cancer tissues compared to that in 12 non-cancerous gastric tissues. Transcript levels were normalized to U6 expression. Boundaries of boxes represent lower and upper quartiles, respectively. Lines within boxes and whiskers denote median and extremum, respectively. P < 0.001, 2-tailed Student’s t-test. b Kaplan–Meier analysis of 5-year overall survival curves of patients with gastric cancer with high miR-501-5p expression (> median, n = 56) versus low miR-501-5p expression (< median, n = 56) [hazard ratio (HR) = 2.413; 95% confidence interval (CI): 1.453–4.008]. P < 0.001, log-rank test