Fig. 3
miR-501-5p enhances the stem cell-like phenotype in gastric cancer cells. a Representative micrographs of tumor spheres formed by indicated cells. b Histograms showing the mean number of spheres formed by the indicated cells from different passages. c The fold change in the number of cells per sphere on the indicated days. d Real-time PCR analysis revealed that miR-501-5p regulates the expression levels of numerous stem cell regulators. The pseudocolors represent the intensity scale of expression in miR-501-5p vs. control-transfected cells or antagomiR-501-5p vs. control-transfected cells generated by log2 transformation. Error bars represent the mean ± s.d. of three independent experiments. * P < 0.05