Fig. 2

Micro-CT-scan rendering and corresponding gross appearance of hepatocellular carcinomas (HCC) in Trim24 ^L2/L2Alb-Cre mice. a Hyperdense, hypervascular nodule in the left liver lobe (arrowhead). b Isodense nodule, with distinguished vascular enhancement ring in the left liver lobe (arrowheads). c Presence in the right median liver lobe of a hypervascular, isodense nodule [1] and in the left median liver lobe of a hypodense nodule [2]. d Multifocal HCC with three well-delineated, hypodense nodules [1–3]. e Multifocal HCC with multiple isodense nodules with an average diameter of 3 to 4 mm; only one tumor [1] located in the right liver lobe had been identified by micro-CT-scan imaging (vertical diameter shown). f Multifocal HCC with multiple hypodense nodules, isodense nodules and isodense nodules with vascular enhancement ring [1–7] – 3 mm in diameter, with edges difficult to evaluate by micro-CT-scan imaging and at dissection